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PMS

 PMS ? 95% of women experience some premenstrual discomfort

? 35% of women have lifestyle disrupting symptoms

Causes of PMS ? 5-10 days before menses ? plasma estrogens are elevated ? plasma progesterone levels are reduced ? 6-9 days before menses ? follicle stimulating hormone (FSH) levels are elevated ? 2-8 days before menses ? aldosterone levels are marginally elevated ? Prolactin levels are elevated in most PMS patients PMS Symptomatic Groups

? PMS-A (Anxiety) ? PMS-C (Cravings) ? PMS-D (Depression) ? PMS-H (Hyperhydration) PMS-A (Anxiety) Symptoms

? Anxiety ? Irritability ? Mood swings ? Increased appetite PMS-A (Anxiety)

? Occurs in 65-75% of PMS ? Cause is high estrogen and low progesterone ratio levels ? High ratio thought to inhibit endorphin release ? Adrenaline/noradrenaline/seratonin (elevated levels) ? Dopamine/phenylalanine (decreased levels) PMS-C (Cravings) Symptoms

? Increased appetite ? Headache ? Fatigue ? Dizziness/fainting ? Palpitations PMS-C (Cravings)

? Occurs in 24-35% of PMS ? Possibly caused by low prostaglandins and increased carbohydrate tolerance ? Glucose tolerance tests show flattening of curve (indicates of excessive insulin response) PMS-D (Depression) Symptoms

? Depression ? Crying ? Forgetfulness ? Confusion ? Insomnia PMS-D (Depression)

? Occurs the least in PMS ? Mechanisms include low estrogen and high progesterone ? Heavy metal toxicity (especially lead) may play role in estrogen receptor blockade, mimicking low estrogenic symptoms ? Depleted magnesium may also contribute PMS-H (Hyperhydration) Symptoms

? Fluid retention ? Swollen extremities ? Breast tenderness ? Abdominal bloating

PMS-H (Hyperhydration) ? Occurs in 65-72% of PMS ? Cause is excess aldosterone, possibly due to ? stress ? excess estrogen ? dopamine deficiencies ? chronic depletion of magnesium Women Experiencing PMS:

Nutritional Correlation ? Refined sugar + 275% ? Dairy products + 79% ? Sodium + 78% ? Refined carbohydrates + 62% ? Manganese - 77% ? Iron - 53% ? Zinc - 52% Phytoestrogens

Isoflavones ? Countries with traditional diet rich in soy foods (China & Japan) have low incidents of menstrual/menopausal complaints ? Thought to protect women because of isoflavones? weaker estrogen-like effect ? Bind to estrogen sites when levels of estrogen drop, thereby decreasing rate of decline of estrogen activity in body

Food Sources of Isoflavones ? Soybean Products ? milk, tofu, miso ? Legumes and Nuts ? sugar snap peas, green peas, split peas, lentils, peanuts, dried beans, green beans, garbanzo beans

PMS Supplement Suggestions ? Establish if dysbiosis exists ? Correct bowel disturbance ? Acidophilus/bifidus ? Cat?s claw ? Garlic ? Grapefruit seed extract ? Olive leaf

PMS Nutritional Supplement Suggestions ? Magnesium ? Vitamin B complex and folic acid reduce cardiovascular disease risk ? Borage oil/gamma linolenic acid (GLA) ? Adrenal complex ? Soy isoflavones

PMS Botanical Supplement Suggestions ? Chasteberry ? Dong quai ? Milk thistle ? N-Acetyl Cysteine

PMS Homeopathic Supplement Suggestions ? Lachesis ? Pulsatilla nigricans ? Sepia ? Sanguinaria

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